FOXO4-DRI
Also known as: FOXO4-D-Retro-Inverso, Proxofim
D-retro-inverso peptide that disrupts FOXO4-p53 interaction in senescent cells, triggering apoptosis of senescent cells (senolytic).
- Typical dose
- 2.5 mg – 10 mg
- Frequency
- twice weekly
- Route
- Subcutaneous
- Half-life
- 7 hours
- Routes
- Subcutaneous
- Status
- Research chemical
Benefits
- Senescent cell clearance
- Anti-aging
- Tissue rejuvenation
- Restored fur density in aged mice
Dosing
A common research range for FOXO4-DRI is 2.5 mg to 10 mg twice weekly. Experimental; 3-week cycles; very expensive. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Reconstitution
A typical reconstitution for FOXO4-DRI is 10 mg of peptide in 2 mL of bacteriostatic water, giving roughly 5 mg per mL. Vial's built-in calculator works out the exact syringe draw for any vial size and dose.
Half-life
FOXO4-DRI has an approximate half-life of 7 hours. Vial plots the real concentration curve from your logged doses so you can see peak windows and when levels taper.
Storage
2-8°C; fragile peptide.
Reported side effects
- Unknown long-term human profile
- Theoretical tissue effects
Contraindications
- Cancer
- Immunosuppression
- Pregnancy
Commonly stacked with
Track FOXO4-DRI with Vial
Vial logs every FOXO4-DRI dose, plots its half-life curve, calculates reconstitution math, and keeps your whole protocol on schedule — on-device and private. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. FOXO4-DRI is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.