MOTS-c
Also known as: Mitochondrial ORF of the 12S rRNA Type-C
Mitochondrial-derived peptide that activates AMPK; exercise mimetic improving insulin sensitivity, fat metabolism, and cellular stress resistance.
- Typical dose
- 2.5 mg – 10 mg
- Frequency
- twice weekly
- Route
- Subcutaneous
- Half-life
- 1.5 hours
- Routes
- Subcutaneous
- Status
- Research chemical
Benefits
- Exercise mimetic
- Insulin sensitivity
- Fat metabolism enhancement
- Mitochondrial function
- Aging muscle support
Dosing
A common research range for MOTS-c is 2.5 mg to 10 mg twice weekly. 5mg 2-3x/week; can be cycled 4 weeks on, 2 off. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Reconstitution
A typical reconstitution for MOTS-c is 10 mg of peptide in 2 mL of bacteriostatic water, giving roughly 5 mg per mL. Vial's built-in calculator works out the exact syringe draw for any vial size and dose.
Half-life
MOTS-c has an approximate half-life of 1.5 hours. Vial plots the real concentration curve from your logged doses so you can see peak windows and when levels taper.
Storage
2-8°C post-reconstitution.
Reported side effects
- Injection site irritation
- Fatigue (initial)
Contraindications
- Pregnancy
Commonly stacked with
Track MOTS-c with Vial
Vial logs every MOTS-c dose, plots its half-life curve, calculates reconstitution math, and keeps your whole protocol on schedule — on-device and private. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. MOTS-c is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.