Gonadorelin
Also known as: GnRH, LHRH, Factrel
Synthetic gonadotropin-releasing hormone; pulsatile delivery stimulates LH/FSH for natural testosterone production.
- Typical dose
- 50 mcg – 200 mcg
- Frequency
- twice daily
- Route
- Subcutaneous
- Half-life
- 4 minutes
- Routes
- Subcutaneous, Intramuscular
- Status
- FDA-approved (diagnostic; Factrel discontinued but generics available); off-label for fertility
Benefits
- Maintains natural testosterone
- Fertility preservation on TRT
- Testicular volume preservation
- HPG axis support
Dosing
A common research range for Gonadorelin is 50 mcg to 200 mcg twice daily. Used alongside TRT to maintain fertility; pulsatile preferred. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Reconstitution
A typical reconstitution for Gonadorelin is 2 mg of peptide in 2 mL of bacteriostatic water, giving roughly 1 mg per mL. Vial's built-in calculator works out the exact syringe draw for any vial size and dose.
Half-life
Gonadorelin has an approximate half-life of 4 minutes. Vial can display informational half-life estimates when supported data is available. These estimates are not measured blood concentrations or dosing instructions.
Storage
2-8°C post-reconstitution; use within 14 days.
Reported side effects
- Headache
- Nausea
- Flushing
- Injection site reactions
Contraindications
- Hormone-sensitive cancers
Commonly stacked with
Track Gonadorelin with Vial
Vial logs every Gonadorelin dose, organizes your schedule, and offers reconstitution math and supported half-life estimates. Tracking records stay on your device. A Vial Pro subscription is required. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. Gonadorelin is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.