Leuphasyl
Also known as: Pentapeptide-18
Enkephalin-mimetic peptide that binds opioid receptors on muscle cells, reducing acetylcholine release; relaxes facial muscles topically.
- Typical dose
- 0 mcg
- Frequency
- twice daily
- Route
- Td
- Half-life
- 8 hours
- Routes
- Td
- Status
- Cosmetic ingredient
Benefits
- Expression wrinkle reduction
- Muscle relaxation (topical)
- Synergistic with Argireline
- Non-invasive anti-aging
Dosing
A common research range for Leuphasyl is 0 mcg twice daily. TOPICAL ONLY: not injectable or oral. 2-5% in serum; best combined with Argireline. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Half-life
Leuphasyl has an approximate half-life of 8 hours. Vial can display informational half-life estimates when supported data is available. These estimates are not measured blood concentrations or dosing instructions.
Storage
Room temperature.
Reported side effects
- Skin irritation (rare)
Commonly stacked with
Track Leuphasyl with Vial
Vial logs every Leuphasyl dose, organizes your schedule, and offers reconstitution math and supported half-life estimates. Tracking records stay on your device. A Vial Pro subscription is required. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. Leuphasyl is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.