Matrixyl
Also known as: Palmitoyl Pentapeptide-4, Pal-KTTKS
Lipopeptide that stimulates collagen I, III, and IV synthesis plus fibronectin production; signals skin repair via TGF-β pathway activation.
- Typical dose
- 0 mcg
- Frequency
- twice daily
- Route
- Td
- Half-life
- 8 hours
- Routes
- Td
- Status
- Cosmetic ingredient
Benefits
- Collagen synthesis stimulation
- Wrinkle depth reduction
- Skin firmness improvement
- Synergy with retinol
Dosing
A common research range for Matrixyl is 0 mcg twice daily. TOPICAL ONLY: not injectable or oral. 2-5% in serum or moisturizer. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Half-life
Matrixyl has an approximate half-life of 8 hours. Vial plots the real concentration curve from your logged doses so you can see peak windows and when levels taper.
Storage
Room temperature.
Reported side effects
- Generally well-tolerated
- Mild redness on sensitive skin
Commonly stacked with
Track Matrixyl with Vial
Vial logs every Matrixyl dose, plots its half-life curve, calculates reconstitution math, and keeps your whole protocol on schedule — on-device and private. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. Matrixyl is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.