Melanotan I
Also known as: Afamelanotide, CUV1647, NDP-MSH
MC1R-selective alpha-MSH analog; stimulates eumelanin production for photoprotective tanning without UV exposure.
- Typical dose
- 500 mcg – 1 mg
- Frequency
- once daily
- Route
- Subcutaneous
- Half-life
- 30 minutes
- Routes
- Subcutaneous
- Status
- FDA-approved (implant) for erythropoietic protoporphyria (EPP)
Benefits
- Skin tanning without UV
- Photoprotection for EPP
- Vitiligo repigmentation
- More selective than MT-II
Dosing
A common research range for Melanotan I is 500 mcg to 1 mg once daily. 10-day loading protocol, then maintenance. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Reconstitution
A typical reconstitution for Melanotan I is 10 mg of peptide in 2 mL of bacteriostatic water, giving roughly 5 mg per mL. Vial's built-in calculator works out the exact syringe draw for any vial size and dose.
Half-life
Melanotan I has an approximate half-life of 30 minutes. Vial plots the real concentration curve from your logged doses so you can see peak windows and when levels taper.
Storage
2-8°C post-reconstitution.
Reported side effects
- Nausea
- Facial flushing
- Mole darkening
Contraindications
- Melanoma history
- Pregnancy
Track Melanotan I with Vial
Vial logs every Melanotan I dose, plots its half-life curve, calculates reconstitution math, and keeps your whole protocol on schedule — on-device and private. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. Melanotan I is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.