MK-677

Also known as: Ibutamoren, Non-peptide GH secretagogue

Non-peptide small molecule (oral ghrelin receptor agonist): sustained GH elevation without injections. Strictly speaking not a peptide but grouped here because it shares the same GH-stimulation goal as CJC/Ipamorelin and is commonly used alongside peptide protocols.

Frequency: once daily
Route: Oral
Half-life: 5 hours
Routes: Oral
Status: Research chemical: not FDA approved

Track your MK-677 protocol in Vial →

Benefits

GH elevation
Improved sleep
Increased appetite
Convenience (oral)

Dosing

10-25 mg/day oral; take pre-sleep to mitigate hunger. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.

Half-life

MK-677 has an approximate half-life of 5 hours. Vial can display informational half-life estimates when supported data is available. These estimates are not measured blood concentrations or dosing instructions.

Storage

Room temperature, dry place.

Reported side effects

Increased appetite
Water retention
Lethargy
Blood sugar elevation

Contraindications

Diabetes (monitor glucose)
Active malignancy

Commonly stacked with

CJC-1295 (no DAC)Ipamorelin

Track MK-677 with Vial

Vial logs every MK-677 dose, organizes your schedule, and offers reconstitution math and supported half-life estimates. Tracking records stay on your device. A Vial Pro subscription is required. Download Vial on the App Store →

This page is for educational and harm-reduction purposes only. MK-677 is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.