P21
Also known as: P021, CNTF-derived peptide
Nonapeptide (9 amino acids) derived from CNTF; promotes neurogenesis and inhibits leukemia inhibitory factor signaling. BDNF-independent neurotrophic.
- Typical dose
- 300 mcg – 1.2 mg
- Frequency
- once daily
- Route
- Subcutaneous
- Half-life
- 1 hours
- Routes
- Subcutaneous, Intranasal
- Status
- Research chemical
Benefits
- Neurogenesis stimulation
- Anti-Alzheimer's (preclinical)
- Dentate gyrus growth
- Tau phosphorylation reduction
Dosing
A common research range for P21 is 300 mcg to 1.2 mg once daily. Experimental; most research is preclinical. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.
Reconstitution
A typical reconstitution for P21 is 30 mg of peptide in 3 mL of bacteriostatic water, giving roughly 10 mg per mL. Vial's built-in calculator works out the exact syringe draw for any vial size and dose.
Half-life
P21 has an approximate half-life of 1 hours. Vial plots the real concentration curve from your logged doses so you can see peak windows and when levels taper.
Storage
2-8°C post-reconstitution.
Reported side effects
- Unknown long-term profile
- Injection site irritation
Contraindications
- Pregnancy
Commonly stacked with
Track P21 with Vial
Vial logs every P21 dose, plots its half-life curve, calculates reconstitution math, and keeps your whole protocol on schedule — on-device and private. Download Vial on the App Store →
This page is for educational and harm-reduction purposes only. P21 is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.