PT-141

Also known as: Bremelanotide, Vyleesi

Melanocortin-4 receptor agonist: centrally-acting libido and sexual function enhancement.

Typical dose

1.25 mg – 2 mg

Frequency

as needed

Route

Subcutaneous

Half-life

2.7 hours

Routes

Subcutaneous

Status

FDA-approved (Vyleesi for HSDD in premenopausal women)

Benefits

• Increased libido
• Improved sexual function
• Works for both sexes

Dosing

A common research range for PT-141 is 1.25 mg to 2 mg as needed. 45 min before activity; max 1 dose per 24h, max 8 doses/month. These figures are reference points from published literature, not a prescription — your protocol should be set with a licensed provider.

Reconstitution

A typical reconstitution for PT-141 is 10 mg of peptide in 2 mL of bacteriostatic water, giving roughly 5 mg per mL. Vial's built-in calculator works out the exact syringe draw for any vial size and dose.

Half-life

PT-141 has an approximate half-life of 2.7 hours. Vial plots the real concentration curve from your logged doses so you can see peak windows and when levels taper.

Storage

2-8°C post-reconstitution.

Reported side effects

• Nausea
• Flushing
• Headache
• Skin darkening

Contraindications

• Uncontrolled hypertension
• Cardiovascular disease

Track PT-141 with Vial

Vial logs every PT-141 dose, plots its half-life curve, calculates reconstitution math, and keeps your whole protocol on schedule — on-device and private. Download Vial on the App Store →

This page is for educational and harm-reduction purposes only. PT-141 is not FDA-approved for most uses described here. Always consult a licensed physician before starting any peptide protocol. Vial does not sell peptides, recommend vendors, or provide medical advice.